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Kazuhiko ISHIHARA Professor
Kazuhiko ISHIHARA Professor
Design and preparation of cell-inspired polymer biomaterials
  • [MAIL] ishihara@mpc.t.u-tokyo.ac.jp
  • [URL] http://www.mpc.t.u-tokyo.ac.jp

Purpose of Research

We are researching on original polymer biomaterials based on molecular design with strong inspiration from the surface structure of cell membrane, that is, the polymers with phospholipid polar group in the side chain, 2-methacryloyloxyethyl phosphorylcholine (MPC) polymers. They can apply to the surface modification of artificial organs and biomedical devices. In fact, implantable artificial heart and artificial hip joint with the MPC polymers have been used clinically already.

Subjects of Reseach

  • Synthesis of phospholipid polymers and application for biomaterials
  • Characterization of interaction between cell and polymer materials
  • Study on polymeric membranes with permeability for proteins
  • Design of photo-living radical polymerization system and development of functional polymer materials
  • Design of stimuli-responsive polymer materials by biomolecules
  • Study on bio-inspired polymer gel
  • Stabilization of bioactive substances in aqueous solution with phospholipid polymer


Human-friendly medical devices by bioinspired biomaterials