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Masao WASHIZU Professor
Masao WASHIZU Professor
Biomanipulation based on microfabrication
  • [MAIL] washizu@washizu.t.u-tokyo.ac.jp
  • [URL] http://www.washizu.t.u-tokyo.ac.jp/

Purpose of Research

Bio-manipulation of single cell and/or single molecule, based upon electrokinetic effects under microfabricated structures, is developed. The applications for the measurement and modification of cellular functions are studied, including electroporation and electrofusion based on field constriction at micro fabricated orifices, micro-mesh as the scaffold for cellular construction, single molecule epigenomic analysis using optical tweezers.

Subjects of Reseach

  • Molecular manipulation of DNA and its application to gene analysis DNA-based molecular construction
  • Introduction of foreign substances into cells by nano-electroporation and the measurement of cellular response
  • Investigation of and control over higher-order structure of chromosomal DNA
  • Single-molecule manipulation of chromosomal DNA using electroosmotic flow
  • Electrostatic manipulation of liquid droplets for micro-reactor applications


Bio-Nanotechnology based on Microfabrication